Chlorothiazide.
نویسندگان
چکیده
منابع مشابه
Clinical evaluation of chlorothiazide.
CHLOROTHIAZIDE, commercially available as Diuril, was introduced to the general medical profession January 1, 1958. It had been available to clinical investigators during the previous year. In this span it has won wide acceptance as an oral diuretic and antihypertensive agent. These comments should be considered in the light of this relatively brief experience. The chemical structure of chlorot...
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We wish to thank Dr. Wilson for suggesting that the bilateral vocal cord paralysis we reported in a patient with Guillain Barre syndrome may have resulted from trauma secondary to intubation with a cuffinflated endotracheal tube. Although this explanation could have contributed to the paralysis, we believe it was primarily the result of the Guillain Barr6 syndrome because: 1. Prior to intubatio...
متن کاملChlorothiazide in hypertensive and normotensive patients.
Chlorothiazide was synthesized by Novello and Sprague’ and found to be a potent, orally effective diuretic and saluretic agent by Beyer, Baer, RUSSO, and Haimbach.’ Ford, Afoyer, and Spurr3 have reported on its diuretic and saluretic properties in patients with edema. Because of its pronounced saluretic action a clinical trial of this agent was undertaken in hypertensive patients. The present r...
متن کاملOn the hypocalciuric action of chlorothiazide.
Clearance experiments were performed in female mongrel dogs, either intact or thyro-parathy-roidectomized (T-PTX), under pentobarbital anesthesia, to examine the unusual hypocalciuric property of thiazide diuretics. The relationship between calcium clearance (C(Ca)) and sodium clearance (C(Na)) was determined in normal dogs, C(Ca) = 0.79 C(Na); constant infusion of chlorothiazide (CTZ) to provi...
متن کاملHemodynamic and hypotensive effects of long-term therapy with chlorothiazide.
T HE value of any drug in the treatment of hypertension rests in the last analysis on the frequeney and magnitude of its depressor effect on the blood pressure and upon whether it corrects the elevated peripheral resistance, characteristic of essential hypertension. Although the hypotensive action of chlorothiazide has been previously studied, -3 nio attempt has yet been made to determine its u...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1982
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1982.tb01332.x